| Date | Opponent | Result | Series | Site |
| Sept. 2 | NORTHWESTERN | L 17-15 | 38-7-2 | NOTRE DAME STADIUM |
| Sept. 9 | Purdue | W 35-28 | 43-21-2 | Ross-Ade Stadium,West Lafayette, IN |
| Sept. 16 | VANDERBILT | W 41-0 | 0-0-0 | NOTRE DAME STADIUM |
| Sept. 23 | TEXAS | W 55-27 | 6-2-0 | NOTRE DAME STADIUM |
| Sept. 30 | Ohio State | L 45-26 | 2-0-0 | Ohio Stadium, Columbus, OH |
| Oct. 7 | Washington | W 29-21 | 2-0-0 | Husky Stadium, Seattle, WA |
| Oct. 14 | Army | W 28-27 | 35-8-4 | Giants Stadium, East Rutherford, NJ |
| Oct. 21 | USC | W 38-10 | 38-23-5 | NOTRE DAME STADIUM |
| Oct. 28 | BOSTON COLLEGE | W 20-10 | 4-2-0 | NOTRE DAME STADIUM |
| Nov. 4 | NAVY | W 35-17 | 58-9-1 | NOTRE DAME STADIUM |
| Nov. 18 | Air Force | W 44-14 | 18-4-0 | Falcon Stadium, Colorado Springs, CO |
| Jan. 2 | Florida State (Orange Bowl) | L 31-26 | 18-4-0 | Orange Bowl, Miami, FL |
| Date | Opponent | Result | Attendance | Site |
| Sept. 3 | Northwestern | W 42-15 | 66,946 (c) | Soldier Field, Chicago, IL |
| Sept. 10 | MICHIGAN | L 24-26 | 59,075 (c) | NOTRE DAME STADIUM |
| Sept. 17 | Michigan State | W 21-20 | 74,183 (c) | Spartan Stadium, East Lansing, MI |
| Sept. 24 | PURDUE | W 39-21 | 59,075 (c) | NOTRE DAME STADIUM |
| Oct. 1 | STANFORD | W 34-15 | 59,075 (c) | NOTRE DAME STADIUM |
| Oct. 8 | Boston College | L 11-30 | 44,500 (c) | Alumni Stadium, Chestnut Hill, MA |
| Oct. 15 | BYU | L 14-21 | 59,075 (c) | NOTRE DAME STADIUM |
| Oct. 29 | NAVY | W 58-21 | 59,075 (c) | NOTRE DAME STADIUM |
| Nov. 12 | Florida State | L 16-23 | 72,868 (c) | Citrus Bowl, Orlando, FL |
| Nov. 19 | AIR FORCE | W 42-30 | 59,075 (c) | NOTRE DAME STADIUM |
| Nov. 26 | USC | T 17-17 | 90,217 (c) | Los Angeles Coliseum, Los Angeles, CA |
| Jan. 2 | Colorado (Fiesta Bowl) | L 24-41 | 73,698 (c) | Sun Devil Stadium, Tempe, AZ |